DMSO 101: Five Things to Know

Dimethyl sulfoxide, known commonly as DMSO, is a compound renowned for its unique properties and diverse applications. From scientific research to potential therapeutic uses, DMSO has drawn attention across various fields. This blog post aims to introduce you to the top things you need to know about DMSO, offering an overview of this fascinating compound.


1. Pain and Inflammation Management: DMSO has been researched for its potential anti-inflammatory and analgesic properties. It is critical to note that the FDA has not approved DMSO for these uses, and its application should be under medical supervision. In 1978, the FDA approved a 50% DMSO solution for intravesicular administration under the brand name Rimso-50 (NDA#017788) for interstitial cystitis. Other than the generic version approved in 2002, this remains the only approved human indication.


2. Membrane Penetration: One of DMSO's standout properties is its ability to penetrate skin and other biological membranes. This characteristic has prompted exploration into its use as a transdermal drug delivery agent. By transporting drugs through biological barriers, DMSO may enhance the bioavailability and efficacy of certain medications.


3. Inflammation Management: Inflammation is a body's natural response to injury or infection. However, excessive or chronic inflammation can lead to further complications. DMSO has potent anti-inflammatory properties, making it a preferred choice for treating conditions like arthritis in animals. Its ability to penetrate skin and other tissues allows it to deliver its anti-inflammatory benefits deeply and effectively. DMSO has been the "go-to" choice for Veterinarians for decades.


4. Chemical Reactions: The polar nature of DMSO allows it to serve as an effective reagent in certain chemical reactions. Its oxidizing properties aid in the synthesis of various organic compounds, thus widening its application scope.


5. Cryopreservation: DMSO's utility extends into biological and medical research as a cryoprotectant. It is commonly used to protect cells and tissues from damage during freezing and thawing processes. This property makes DMSO an indispensable tool in labs worldwide for preserving biological samples.


In conclusion, DMSO is a versatile and fascinating compound, with diverse applications spanning various sectors. Its unique properties make it a subject of ongoing interest to researchers and industry professionals alike. As we continue to study DMSO, we look forward to uncovering even more about its potential.


FDA Disclaimer: The statements made in this blog post have not been evaluated by the Food and Drug Administration. DMSO is not intended to diagnose, treat, cure, or prevent any disease. 

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